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    当前位置:首页公司新闻Biomedica 公司NT-proBNP ELISA Kit 简介

    Biomedica 公司NT-proBNP ELISA Kit 简介

    更新时间:2014-03-23点击次数:1223

    NT-proBNP ELISA Kit (Cat.No.SK-1204)

    为什么要检测NT-proBNP ?

    NT-proBNP proBNP分解后的76氨基酸片段。proBNP是心脏为弥补收缩无力而增大时,心壁被拉伸时由心脏释放到血液中的化学物质。一旦从心脏释放到血液中,proBNP就会分割为NT-proBNPBNP。由于NT-proBNP的半衰期为120min,相比之下,BNP的半衰期仅20min。所以NT-proBNP可追踪的时间可达24hBNPzui多可监测的时间为1h。因此,检测血清/血浆中的NT-proBNP稳定性更好,检测结果更可靠,是有效的心衰检测工具。

    应用领域:

    1. 心脏衰竭、急性心肌梗死(左心室功能不全)
    2. 肾衰竭
    3. 肥胖症和糖尿病
    4. 各种形式的继发性高血压
    5. 心衰患者的疗效监测

    产品优势:

    1. 性价比高
    2. 可用于每个实验室或开放实验室
    3. CE 标志-可用于临床诊断
    4. 简单-传统96孔板
    5. 动态检测范围广-可用于早期心衰检测

    试剂盒特点:

    检测方法:夹心ELISA,HRP/TMB显色,12x8 板条

    样本类型:血清

    样品量:50ul/test

    标准品范围:0-640 pmol/L

    检测灵敏度:3pmol/L

    孵育条件:3h/30min

    单位换算:1pmol/L=8.475pg/ml

    参考文献:

    1

    Infliximab Treatment Increases Left Ventricular Ejection Fraction in Patients with Rheumatoid Arthritis: Assessment of Heart Function by Echocardiography, Endothelin 1, Interleukin 6, and NT-pro Brain Natriuretic Peptide. PRZEMYSLAW J,et al. J Rheumatol, Apr 2012; 39: 701 - 706.

    2

    Left Ventricular Function Impairment in Patients With Normal-Weight Obesity:

    Contribution of Abdominal Fat Deposition, Profibrotic State, Reduced Insulin

    Sensitivity, and Proinflammatory Activation. Wojciech Kosmala,et al. Circ Cardiovasc Imaging, May 2012; 5: 349 - 356.

    3

    Prognostic value of left atrial expansion index and exercise-induced change in atrial natriuretic peptide as long-term predictors of atrial fibrillation recurrence..Malini Govindan,et al. Europace, Sep 2012; 14: 1302 - 1310.

    4

    Osteopontin-mediated myocardial fibrosis in heart failure: a role for lysyl

    oxidase? Begoña López,et al. Cardiovasc Res, Jul 2013; 99: 111 - 120. 

    5

    High-sensitivity troponin assay improves prediction of cardiovascular risk in

    patients with cerebral ischaemia. Raoul Stahrenberg,et al. J. Neurol. Neurosurg. Psychiatry, May 2013; 84: 479 - 487.

    6

    Translational phases of evidence in a prognostic biomarker: a systematic review and meta-analysis of natriuretic peptides and the prognosis of stable coronary disease. Shailen Sutaria,et al. Heart, Apr 2012; 98: 615 - 622. 

    7

    Prognostic impact of body mass index in patients undergoing coronary artery

    bypass surgery. Shih-Hsien Sung,et al. Heart, Apr 2011; 97: 648 - 654.

    8

    Troponin T, N-terminal pro natriuretic peptide and a patent ductus arteriosus

    scoring system predict death before discharge or neurodevelopmental outcome at 2 years in preterm infants. Afif F EL-Khuffash,et al. Arch. Dis. Child. Fetal Neonatal Ed., Mar 2011; 96: F133 - F137. 

    9

    Multidimensional assessment of older people with asthma and COPD: clinical

    management and health status. Vanessa M. McDonald,et al. Age Ageing, Jan 2011; 40: 42 – 49

    10

    Diagnostic value of NT-proBNP in identifying aortic stenosis patients with heart failure. C Wu,et al. Zhonghua Xin Xue Guan Bing Za Zhi, Jul 2010; 38(7): 579-83.

    11

    Pulmonary arterial hypertension in rheumatic mitral stenosis: does it affect right

    ventricular function and outcome after mitral valve replacement? Shantanu Pande,et al. Interact CardioVasc Thorac Surg, Sep 2009; 9: 421 - 425

    12

    Pulmonary arterial hypertension in rheumatic mitral stenosis: does it affect right

    ventricular function and outcome after mitral valve replacement? Shantanu Pande,et al. Interactive CardioVascular and Thoracic Surgery, Sep 2009; 9: 421 - 425.

    13

    Effect of piboserod, a 5-HT4 serotonin receptor antagonist, on left ventricular

    function in patients with symptomatic heart failure. John K. Kjekshus,et al. Eur J Heart Fail, Aug 2009; 11: 771 – 778

    14

    Prevalence of Left Ventricular Diastolic Dysfunction in a General Population. Tatiana Kuznetsova,et al. Circ Heart Fail, Mar 2009; 2: 105 - 112.

     

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